There are a few ways to delete NPCs in Skyrim. The easiest way is to use the console command “setstage npc_delete 0”. This will delete all the NPCs in the current scene. The second way is to use the “deleteNPC” spell. This spell will delete all the NPCs in a specific area of Skyrim, and it will also delete any items they may have been carrying. The final way is to use the “killallNPCs” command. This command will kill all the NPCs in Skyrim, regardless of whether they are currently alive or not.